Endocrine Abstracts

Background: Distinction of benign testicular adrenal rest tumours (TART) and potentially malign Leydig cell tumors (LCT) is challenging but important to prevent unnecessary surgery of TART. Ultrasound or magnetic resonance imaging can reliably detect but not distinguish between both tumour entities.Methods: Functional imaging results using the specific CYP11B1/2-inhibitor 123I-IMAZA were investigated in seven adult male patients with classic c...

Context: The occurrence of different subtypes of endogenous Cushing’s syndrome (CS) in single individuals is extremely rare. We here present the case of a female patient who was successfully cured from adrenal CS 4 years before being diagnosed with Cushing's disease (CD).Case Description: A 50-year-old female was diagnosed with ACTH-independent CS and a left-sided adrenal adenoma in January 2015. After adrenalectomy and histopathological co...

Background: Current parameters of conventional radiology have several limitations in defining the nature of adrenal masses. Radiomics, or texture analysis, has shown high diagnostic performance in recent pilot studies, although confirmatory studies are needed. Moreover, the effect of combination of radiomics with hormonal secretion on diagnostic performance is poorly explored.Aim: To evaluate the accuracy of radiomics in predicting adrenal masses nature ...

Adrenal tumours are frequently detected by conventional cross-sectional imaging, which, however, has limited specificity in identifying the most prevalent tumour type, benign, non-functional adrenocortical adenomas (ACA) not requiring surgery. We assessed the diagnostic accuracy of adrenal molecular imaging with [18F]Fluorodeoxyglucose-positron emission tomography (FDG-PET) and [123I]Iodometomidate-single photon emission tomography (IMTO-SPECT). We perfor...